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SMILES: Cc1ccc(cc1Nc1ncc2ccn(-c3ccccn3)c2n1)-c1cnc2ccccc2n1

InChI Key: InChIKey=KVYYSUPOTZCZAO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181986   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50181986
PNG
(CHEMBL206853 | N-(2-methyl-5-(quinoxalin-2-yl)phen...)
Show SMILES Cc1ccc(cc1Nc1ncc2ccn(-c3ccccn3)c2n1)-c1cnc2ccccc2n1
Show InChI InChI=1S/C26H19N7/c1-17-9-10-18(23-16-28-20-6-2-3-7-21(20)30-23)14-22(17)31-26-29-15-19-11-13-33(25(19)32-26)24-8-4-5-12-27-24/h2-16H,1H3,(H,29,31,32)
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n/an/a 600n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair