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SMILES: COc1cc(Nc2ncc3CCC(O)N(c4ccccn4)c3n2)cc(OC)c1OC

InChI Key: InChIKey=XPOCZDMBFFIEAX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182006   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50182006
PNG
(8-(pyridin-2-yl)-2-(3,4,5-trimethoxyphenylamino)-5...)
Show SMILES COc1cc(Nc2ncc3CCC(O)N(c4ccccn4)c3n2)cc(OC)c1OC
Show InChI InChI=1S/C21H23N5O4/c1-28-15-10-14(11-16(29-2)19(15)30-3)24-21-23-12-13-7-8-18(27)26(20(13)25-21)17-6-4-5-9-22-17/h4-6,9-12,18,27H,7-8H2,1-3H3,(H,23,24,25)
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MMDB

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Article
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n/an/a 200n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair