BDBM50182158 5-methylsulfanyl-4-phenylmethanesulfonyl-thiophene-2-carboxamidine::CHEMBL383619

SMILES: CSc1sc(cc1S(=O)(=O)Cc1ccccc1)C(N)=N

InChI Key: InChIKey=OQOPWZDNMNDNCM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50182158 (5-methylsulfanyl-4-phenylmethanesulfonyl-thiophene...) Show SMILES CSc1sc(cc1S(=O)(=O)Cc1ccccc1)C(N)=N Show InChI InChI=1S/C13H14N2O2S3/c1-18-13-11(7-10(19-13)12(14)15)20(16,17)8-9-5-3-2-4-6-9/h2-7H,8H2,1H3,(H3,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of C1S				Bioorg Med Chem Lett 16: 2200-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.036 BindingDB Entry DOI: 10.7270/Q2251HSV
					More data for this Ligand-Target Pair