BDBM50182175 4-(1-methyl-1H-imidazole-2-sulfonyl)-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL380146

SMILES: CSc1sc(cc1S(=O)(=O)c1nccn1C)C(N)=N

InChI Key: InChIKey=QLVPWONQUDDSHJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50182175 (4-(1-methyl-1H-imidazole-2-sulfonyl)-5-methylsulfa...) Show SMILES CSc1sc(cc1S(=O)(=O)c1nccn1C)C(N)=N Show InChI InChI=1S/C10H12N4O2S3/c1-14-4-3-13-10(14)19(15,16)7-5-6(8(11)12)18-9(7)17-2/h3-5H,1-2H3,(H3,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of C1S				Bioorg Med Chem Lett 16: 2200-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.036 BindingDB Entry DOI: 10.7270/Q2251HSV
					More data for this Ligand-Target Pair