BDBM50182510 CHEMBL202582::N-(3-(2-methylbenzamido)phenyl)thiophene-2-carboxamide

SMILES: Cc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccs2)c1

InChI Key: InChIKey=LKPHCDSDJRIFEE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50182510 (CHEMBL202582 | N-(3-(2-methylbenzamido)phenyl)thio...) Show SMILES Cc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccs2)c1 Show InChI InChI=1S/C19H16N2O2S/c1-13-6-2-3-9-16(13)18(22)20-14-7-4-8-15(12-14)21-19(23)17-10-5-11-24-17/h2-12H,1H3,(H,20,22)(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of 15-hLO				J Med Chem 49: 1356-63 (2006) Article DOI: 10.1021/jm050639j BindingDB Entry DOI: 10.7270/Q2057FH3
					More data for this Ligand-Target Pair
12-Lipoxygenase (12-LOX) (Homo sapiens (Human))	BDBM50182510 (CHEMBL202582 | N-(3-(2-methylbenzamido)phenyl)thio...) Show SMILES Cc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccs2)c1 Show InChI InChI=1S/C19H16N2O2S/c1-13-6-2-3-9-16(13)18(22)20-14-7-4-8-15(12-14)21-19(23)17-10-5-11-24-17/h2-12H,1H3,(H,20,22)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of 12-hLO				J Med Chem 49: 1356-63 (2006) Article DOI: 10.1021/jm050639j BindingDB Entry DOI: 10.7270/Q2057FH3
					More data for this Ligand-Target Pair