BDBM50182558 CHEMBL3819608

SMILES: Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5N(CCOc5c4c3)C(=O)C3CC3)n2c1

InChI Key: InChIKey=ZRIJONWBCNFMEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182558 (CHEMBL3819608) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5N(CCOc5c4c3)C(=O)C3CC3)n2c1 Show InChI InChI=1S/C25H20FN7O2S/c1-31-12-16(10-28-31)15-8-19(26)23-29-30-25(33(23)13-15)36-17-4-5-20-18(9-17)22-21(11-27-20)32(6-7-35-22)24(34)14-2-3-14/h4-5,8-14H,2-3,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) incubated for 1 hr by spectrophotometric analysis				Bioorg Med Chem 24: 3483-93 (2016) BindingDB Entry DOI: 10.7270/Q29G5PQT
					More data for this Ligand-Target Pair