BDBM50182600 1-(4-(4-benzoylbenzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone::CHEMBL201808

SMILES: COc1c(O)c(C(C)=O)c(OCc2ccc(cc2)C(=O)c2ccccc2)c2ccoc12

InChI Key: InChIKey=YUUWUJYKCMALTL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.3 (Mus musculus)	BDBM50182600 (1-(4-(4-benzoylbenzyloxy)-6-hydroxy-7-methoxybenzo...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(cc2)C(=O)c2ccccc2)c2ccoc12 Show InChI InChI=1S/C25H20O6/c1-15(26)20-22(28)25(29-2)24-19(12-13-30-24)23(20)31-14-16-8-10-18(11-9-16)21(27)17-6-4-3-5-7-17/h3-13,28H,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of mouse Kv1.3 channel expressed in L929 cells				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair