BDBM50182603 1-(4-(4-bromobenzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone::CHEMBL205020

SMILES: COc1c(O)c(C(C)=O)c(OCc2ccc(Br)cc2)c2ccoc12

InChI Key: InChIKey=ULPCMPOKSGXWOI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.3 (Mus musculus)	BDBM50182603 (1-(4-(4-bromobenzyloxy)-6-hydroxy-7-methoxybenzofu...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Br)cc2)c2ccoc12 Show InChI InChI=1S/C18H15BrO5/c1-10(20)14-15(21)18(22-2)17-13(7-8-23-17)16(14)24-9-11-3-5-12(19)6-4-11/h3-8,21H,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of mouse Kv1.3 channel expressed in L929 cells				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair