BDBM50183095 4-tert-butyl-N-(2-isopropylphenyl)thiazol-2-amine::CHEMBL206788

SMILES: CC(C)c1ccccc1Nc1nc(cs1)C(C)(C)C

InChI Key: InChIKey=XGRAMFLJGHKCSV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50183095 (4-tert-butyl-N-(2-isopropylphenyl)thiazol-2-amine ...) Show SMILES CC(C)c1ccccc1Nc1nc(cs1)C(C)(C)C Show InChI InChI=1S/C16H22N2S/c1-11(2)12-8-6-7-9-13(12)17-15-18-14(10-19-15)16(3,4)5/h6-11H,1-5H3,(H,17,18)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]TARC from CCR4 expressed in human CEM cell line				Bioorg Med Chem Lett 16: 2800-3 (2006) Article DOI: 10.1016/j.bmcl.2006.01.126 BindingDB Entry DOI: 10.7270/Q2X63MHC
					More data for this Ligand-Target Pair