BDBM50183163 CHEMBL208070::N-(4-fluoro-2-(trifluoromethyl)benzyl)-N-(2-isopropoxyethyl)piperidin-4-amine tartaric acid salt

SMILES: CC(C)OCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1

InChI Key: InChIKey=OKTPOAKUYYFNLE-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50183163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50183163 (CHEMBL208070 | N-(4-fluoro-2-(trifluoromethyl)benz...) Show SMILES CC(C)OCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C18H26F4N2O/c1-13(2)25-10-9-24(16-5-7-23-8-6-16)12-14-3-4-15(19)11-17(14)18(20,21)22/h3-4,11,13,16,23H,5-10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50183163 (CHEMBL208070 | N-(4-fluoro-2-(trifluoromethyl)benz...) Show SMILES CC(C)OCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C18H26F4N2O/c1-13(2)25-10-9-24(16-5-7-23-8-6-16)12-14-3-4-15(19)11-17(14)18(20,21)22/h3-4,11,13,16,23H,5-10,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair