BDBM50183194 2-(1-mesityl-1H-tetrazol-5-ylthio)-N-(2-methyl-4-nitrophenyl)acetamide::CHEMBL377310

SMILES: Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1C)[N+]([O-])=O

InChI Key: InChIKey=XDKDRKQXCXAISG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50183194 (2-(1-mesityl-1H-tetrazol-5-ylthio)-N-(2-methyl-4-n...) Show SMILES Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1C)[N+]([O-])=O |(-7.4,-3.06,;-7.06,-1.55,;-8.2,-.51,;-7.87,.99,;-9.01,2.03,;-6.4,1.46,;-5.26,.43,;-3.8,.9,;-5.59,-1.09,;-6.08,2.97,;-7.11,4.12,;-6.33,5.45,;-4.83,5.13,;-4.67,3.59,;-3.34,2.82,;-2,3.59,;-.67,2.82,;-.67,1.28,;.66,3.58,;2,2.81,;1.99,1.27,;3.32,.5,;4.66,1.27,;4.65,2.81,;3.32,3.58,;3.32,5.12,;5.99,.49,;5.99,-1.05,;7.33,1.26,)| Show InChI InChI=1S/C19H20N6O3S/c1-11-7-13(3)18(14(4)8-11)24-19(21-22-23-24)29-10-17(26)20-16-6-5-15(25(27)28)9-12(16)2/h5-9H,10H2,1-4H3,(H,20,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
MRL Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type Reverse Transcriptase				Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R
					More data for this Ligand-Target Pair