BDBM50183204 CHEMBL208057::N-(2-methyl-4-sulfamoyl-phenyl)-2-[1-(2,4,6-trimethyl-phenyl)-1H-tetrazol-5-ylsulfanyl]-acetamide

SMILES: Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1C)S(N)(=O)=O

InChI Key: InChIKey=NZCOTRJLQYBXMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50183204 (CHEMBL208057 | N-(2-methyl-4-sulfamoyl-phenyl)-2-[...) Show SMILES Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1C)S(N)(=O)=O |(-6.98,-13.11,;-6.65,-11.6,;-7.79,-10.56,;-7.46,-9.06,;-8.59,-8.02,;-5.99,-8.59,;-4.85,-9.62,;-3.39,-9.15,;-5.18,-11.14,;-5.67,-7.08,;-6.69,-5.93,;-5.92,-4.6,;-4.41,-4.92,;-4.26,-6.46,;-2.93,-7.23,;-1.59,-6.46,;-.26,-7.23,;-.26,-8.77,;1.08,-6.47,;2.41,-7.24,;2.4,-8.78,;3.73,-9.55,;5.07,-8.78,;5.07,-7.24,;3.73,-6.47,;3.73,-4.93,;6.4,-9.55,;7.73,-10.32,;5.63,-10.89,;7.18,-8.22,)| Show InChI InChI=1S/C19H22N6O3S2/c1-11-7-13(3)18(14(4)8-11)25-19(22-23-24-25)29-10-17(26)21-16-6-5-15(9-12(16)2)30(20,27)28/h5-9H,10H2,1-4H3,(H,21,26)(H2,20,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
MRL Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type Reverse Transcriptase				Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R
					More data for this Ligand-Target Pair