BDBM50183209 CHEMBL204993::N-(2-chloro-4-nitrophenyl)-2-(1-mesityl-1H-tetrazol-5-ylthio)acetamide

SMILES: Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1Cl)[N+]([O-])=O

InChI Key: InChIKey=OMFUESMBFNGLKS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50183209 (CHEMBL204993 | N-(2-chloro-4-nitrophenyl)-2-(1-mes...) Show SMILES Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1Cl)[N+]([O-])=O |(14.87,-48.33,;15.2,-46.83,;14.07,-45.79,;14.4,-44.28,;13.26,-43.24,;15.86,-43.81,;17,-44.85,;18.47,-44.38,;16.67,-46.36,;16.19,-42.31,;15.16,-41.15,;15.94,-39.82,;17.44,-40.15,;17.6,-41.68,;18.93,-42.45,;20.26,-41.69,;21.6,-42.46,;21.59,-44,;22.93,-41.69,;24.26,-42.46,;24.26,-44,;25.59,-44.78,;26.92,-44.01,;26.92,-42.46,;25.59,-41.7,;25.59,-40.16,;28.26,-44.78,;28.26,-46.32,;29.59,-44.01,)| Show InChI InChI=1S/C18H17ClN6O3S/c1-10-6-11(2)17(12(3)7-10)24-18(21-22-23-24)29-9-16(26)20-15-5-4-13(25(27)28)8-14(15)19/h4-8H,9H2,1-3H3,(H,20,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
MRL Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type Reverse Transcriptase				Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R
					More data for this Ligand-Target Pair