BDBM50183216 2-(1-mesityl-1H-tetrazol-5-ylthio)-N-(3-nitrophenyl)acetamide::CHEMBL381286

SMILES: Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=ATLZPMUUJRAXLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50183216 (2-(1-mesityl-1H-tetrazol-5-ylthio)-N-(3-nitropheny...) Show SMILES Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1cccc(c1)[N+]([O-])=O |(14.54,-25.45,;14.88,-23.95,;13.74,-22.91,;14.07,-21.4,;12.94,-20.36,;15.54,-20.93,;16.68,-21.97,;18.14,-21.49,;16.35,-23.48,;15.86,-19.43,;14.84,-18.27,;15.61,-16.94,;17.12,-17.27,;17.27,-18.8,;18.6,-19.57,;19.94,-18.8,;21.27,-19.58,;21.27,-21.12,;22.6,-18.81,;23.94,-19.58,;23.93,-21.12,;25.26,-21.89,;26.6,-21.13,;26.59,-19.58,;25.26,-18.81,;27.94,-18.8,;29.27,-19.57,;27.93,-17.26,)| Show InChI InChI=1S/C18H18N6O3S/c1-11-7-12(2)17(13(3)8-11)23-18(20-21-22-23)28-10-16(25)19-14-5-4-6-15(9-14)24(26)27/h4-9H,10H2,1-3H3,(H,19,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
MRL Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type Reverse Transcriptase				Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R
					More data for this Ligand-Target Pair