BDBM50183247 2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-chromen-4-one::CHEMBL380864::[4',3''']biflavone

SMILES: O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1

InChI Key: InChIKey=WKIQPLYBWAHSLW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50183247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50183247 (2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-10-3-1-8-23(25)27)20-14-12-19(13-15-20)21-6-5-7-22(16-21)30-18-26(32)24-9-2-4-11-28(24)34-30/h1-18H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of human cloned cPLA2 expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
					More data for this Ligand-Target Pair
Group X secretory phospholipase A2 (Homo sapiens (Human))	BDBM50183247 (2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-10-3-1-8-23(25)27)20-14-12-19(13-15-20)21-6-5-7-22(16-21)30-18-26(32)24-9-2-4-11-28(24)34-30/h1-18H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of human cloned sPLA2-10 expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
					More data for this Ligand-Target Pair
Phospholipase A2 group 1B (Rattus norvegicus)	BDBM50183247 (2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-10-3-1-8-23(25)27)20-14-12-19(13-15-20)21-6-5-7-22(16-21)30-18-26(32)24-9-2-4-11-28(24)34-30/h1-18H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50183247 (2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-10-3-1-8-23(25)27)20-14-12-19(13-15-20)21-6-5-7-22(16-21)30-18-26(32)24-9-2-4-11-28(24)34-30/h1-18H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kangwon National University Curated by ChEMBL					Assay Description Inhibition of sPLA2-2A in HEK293 cell				Bioorg Med Chem Lett 16: 2373-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.117 BindingDB Entry DOI: 10.7270/Q20Z72VZ
					More data for this Ligand-Target Pair