BindingDB PrimarySearch

BDBM50183250 2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one::2-{4-[5-(5,7-dihydroxy-4-oxo-4H-2-chromenyl)-2-hydroxyphenoxy]phenyl}-5,7-dihydroxy-4H-4-chromenone::CHEMBL187504::OCHNAFLAVONE

SMILES: Oc1cc2oc(cc(O)c2c(=O)c1)-c1ccc(Oc2cc(ccc2O)-c2cc(O)c3c(cc(O)cc3=O)o2)cc1

InChI Key: InChIKey=FNCFTPRYGUJRBZ-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50183250
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50183250 (2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of human cloned cPLA2 expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
Yeungnam University Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2 group 1B (Rattus norvegicus)	BDBM50183250 (2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
Yeungnam University Curated by ChEMBL					More data for this Ligand-Target Pair
Group X secretory phospholipase A2 (Homo sapiens (Human))	BDBM50183250 (2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of human cloned sPLA2-10 expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
Yeungnam University Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50183250 (2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kangwon National University Curated by ChEMBL					Assay Description Inhibition of sPLA2-2A in HEK293 cell				Bioorg Med Chem Lett 16: 2373-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.117 BindingDB Entry DOI: 10.7270/Q20Z72VZ
Kangwon National University Curated by ChEMBL					More data for this Ligand-Target Pair