BDBM50183377 CHEMBL383231::methyl 3-[(3-{[2-(methoxycarbonyl)thien-3-yl]amino}-3-oxopropanoyl)amino]thiophene-2-carboxylate
SMILES: COC(=O)c1sccc1NC(=O)CC(=O)Nc1ccsc1C(=O)OC
InChI Key: InChIKey=WZNVWZUBSGPUSQ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cysteine protease falcipain-3 (Plasmodium falciparum) | BDBM50183377 (CHEMBL383231 | methyl 3-[(3-{[2-(methoxycarbonyl)t...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of falcipain3 | J Med Chem 49: 1576-84 (2006) Article DOI: 10.1021/jm0505765 BindingDB Entry DOI: 10.7270/Q2B27W35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM50183377 (CHEMBL383231 | methyl 3-[(3-{[2-(methoxycarbonyl)t...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of falcipain2 | J Med Chem 49: 1576-84 (2006) Article DOI: 10.1021/jm0505765 BindingDB Entry DOI: 10.7270/Q2B27W35 | |||||||||||
More data for this Ligand-Target Pair |