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BDBM50183985 CHEMBL383263::N-methyl-2-(3-(2-(3,4,5-trimethoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenyl)acetamide

SMILES: CNC(=O)Cc1cccc(c1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12

InChI Key: InChIKey=PTTFRUZTSYMLAA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183985   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))
BDBM50183985
PNG
(CHEMBL383263 | N-methyl-2-(3-(2-(3,4,5-trimethoxyp...)
Show SMILES CNC(=O)Cc1cccc(c1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12
Show InChI InChI=1S/C24H25N5O4/c1-25-21(30)11-15-6-5-7-18(10-15)29-9-8-16-14-26-24(28-23(16)29)27-17-12-19(31-2)22(33-4)20(13-17)32-3/h5-10,12-14H,11H2,1-4H3,(H,25,30)(H,26,27,28)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.81E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK


Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair