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SMILES: COC(=O)CNC(=O)c1cccc(n1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12

InChI Key: InChIKey=XONBZWAFRNHYQF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184038   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50184038
PNG
(CHEMBL206927 | methyl 2-(2-(2-(3,4,5-trimethoxyphe...)
Show SMILES COC(=O)CNC(=O)c1cccc(n1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12
Show InChI InChI=1S/C24H24N6O6/c1-33-17-10-15(11-18(34-2)21(17)36-4)27-24-26-12-14-8-9-30(22(14)29-24)19-7-5-6-16(28-19)23(32)25-13-20(31)35-3/h5-12H,13H2,1-4H3,(H,25,32)(H,26,27,29)
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n/an/a 544n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK

Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair