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SMILES: COC(=O)c1cc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc2n1-c1ccccn1

InChI Key: InChIKey=JPZHVTDTKHKWBU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184051   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50184051
PNG
(CHEMBL383460 | methyl 7-(pyridin-2-yl)-2-(3,4,5-tr...)
Show SMILES COC(=O)c1cc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc2n1-c1ccccn1
Show InChI InChI=1S/C22H21N5O5/c1-29-16-10-14(11-17(30-2)19(16)31-3)25-22-24-12-13-9-15(21(28)32-4)27(20(13)26-22)18-7-5-6-8-23-18/h5-12H,1-4H3,(H,24,25,26)
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PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK

Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair