null
SMILES: COC(=O)C1=C([C@H]2c3ccccc3S[C@@]12C(=O)OC)N1CCCCC1
InChI Key: InChIKey=LKDSIRXDWPTAGQ-AUUYWEPGSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50184091 ((2aR,7aR)-2-piperidin-1-yl-2aH-7-thia-cyclobuta[a]...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NIH Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase in 293T cells | Bioorg Med Chem Lett 16: 3034-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.049 BindingDB Entry DOI: 10.7270/Q2DN45VP | |||||||||||
More data for this Ligand-Target Pair |