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SMILES: CC(C)(C)OC(=O)C1=C(C2c3ccccc3SC12C(=O)OC(C)(C)C)N1CCCC1

InChI Key: InChIKey=GRPTXKXXBXTROF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184093   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50184093
PNG
((R,R/S,S)-2-pyrrolidin-1-yl-2aH-7-thia-cyclobuta[a...)
Show SMILES CC(C)(C)OC(=O)C1=C(C2c3ccccc3SC12C(=O)OC(C)(C)C)N1CCCC1 |t:7|
Show InChI InChI=1S/C24H31NO4S/c1-22(2,3)28-20(26)18-19(25-13-9-10-14-25)17-15-11-7-8-12-16(15)30-24(17,18)21(27)29-23(4,5)6/h7-8,11-12,17H,9-10,13-14H2,1-6H3
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PC cid
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UniChem

Similars
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



NIH

Curated by ChEMBL


Assay Description
Inhibition of wild type HIV1 reverse transcriptase in 293T cells

Bioorg Med Chem Lett 16: 3034-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.049
BindingDB Entry DOI: 10.7270/Q2DN45VP
More data for this
Ligand-Target Pair