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SMILES: CCCCN(C)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)nc1)c1ccccc1

InChI Key: InChIKey=QDAFLWYDCROPEM-LJAQVGFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184107   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microsomal triglyceride transfer protein large subunit


(Homo sapiens (Human))		BDBM50184107
PNG
(CHEMBL245300 | N-[(S)-(butyl-methyl-carbamoyl)-phe...)
Show SMILES CCCCN(C)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)nc1)c1ccccc1
Show InChI InChI=1S/C33H31F3N4O3/c1-3-4-20-40(2)32(43)29(23-10-6-5-7-11-23)39-30(41)24-16-19-28(37-21-24)38-31(42)27-13-9-8-12-26(27)22-14-17-25(18-15-22)33(34,35)36/h5-19,21,29H,3-4,20H2,1-2H3,(H,39,41)(H,37,38,42)/t29-/m0/s1
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Article
PubMed
n/an/a 16.9n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of MTP in canine liver microsomes

Bioorg Med Chem Lett 16: 3039-42 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.058
BindingDB Entry DOI: 10.7270/Q2D21X68
More data for this
Ligand-Target Pair