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SMILES: CCNc1ccc(cc1)-c1nc2ccccc2n2cccc12

InChI Key: InChIKey=OEUMSXQHYXCNBG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM50184320 (CHEMBL3823105) Show SMILES CCNc1ccc(cc1)-c1nc2ccccc2n2cccc12 Show InChI InChI=1S/C19H17N3/c1-2-20-15-11-9-14(10-12-15)19-18-8-5-13-22(18)17-7-4-3-6-16(17)21-19/h3-13,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human N-terminal 6-histidine/Avi-tagged recombinant RAD51 expressed in Escherichia coli BL21(DE3) assessed as D-loop formation using 5'...				J Med Chem 59: 4511-25 (2016) BindingDB Entry DOI: 10.7270/Q200041Q
					More data for this Ligand-Target Pair
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM50184320 (CHEMBL3823105) Show SMILES CCNc1ccc(cc1)-c1nc2ccccc2n2cccc12 Show InChI InChI=1S/C19H17N3/c1-2-20-15-11-9-14(10-12-15)19-18-8-5-13-22(18)17-7-4-3-6-16(17)21-19/h3-13,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Escherichia coli BL21(DE3) expressing human N-terminal 6-histidine/Avi-tagged RAD51 binding to 5'-Alexa488-oligo-dT45 ssDNA preincubate...				J Med Chem 59: 4511-25 (2016) BindingDB Entry DOI: 10.7270/Q200041Q
					More data for this Ligand-Target Pair
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM50184320 (CHEMBL3823105) Show SMILES CCNc1ccc(cc1)-c1nc2ccccc2n2cccc12 Show InChI InChI=1S/C19H17N3/c1-2-20-15-11-9-14(10-12-15)19-18-8-5-13-22(18)17-7-4-3-6-16(17)21-19/h3-13,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of RAD51-mediated homologous recombination in human HEK293-DR-GFP cells transfected with pCBASce expressing I-Sce-I after 24 hrs following...				J Med Chem 59: 4511-25 (2016) BindingDB Entry DOI: 10.7270/Q200041Q
					More data for this Ligand-Target Pair