| Reaction Details |
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 | Report a problem with these data |
| Target | DNA repair protein RAD51 homolog 1 |
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| Ligand | BDBM50184320 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1586883 (CHEMBL3824503) |
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| IC50 | 3000±n/a nM |
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| Citation |  Lv, W; Budke, B; Pawlowski, M; Connell, PP; Kozikowski, AP Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51. J Med Chem59:4511-25 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA repair protein RAD51 homolog 1 |
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| Name: | DNA repair protein RAD51 homolog 1 |
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| Synonyms: | RAD51 | RAD51A | RAD51_HUMAN | RECA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36960.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_49168602 |
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| Residue: | 339 |
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| Sequence: | MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL
INIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG
SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL
SGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSA
RQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRL
YLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
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| BDBM50184320 |
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| n/a |
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| Name | BDBM50184320 |
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| Synonyms: | CHEMBL3823105 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N3 |
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| Mol. Mass. | 287.3584 |
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| SMILES | CCNc1ccc(cc1)-c1nc2ccccc2n2cccc12 |
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| Structure | 
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