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BDBM50184386 6-hydroxymethyl-3-[(E)-3-isobutyl-5-methylhexylidene]-6-octanoyloxymethyl-tetrahydro-2-pyranone::CHEMBL205248

SMILES: CCCCCCCC(=O)OCC1(CO)CC\C(=C/CC(CC(C)C)CC(C)C)C(=O)O1

InChI Key: InChIKey=ZRYLKIYLIIRRIN-YDZHTSKRSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184386   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50184386
PNG
(6-hydroxymethyl-3-[(E)-3-isobutyl-5-methylhexylide...)
Show SMILES CCCCCCCC(=O)OCC1(CO)CC\C(=C/CC(CC(C)C)CC(C)C)C(=O)O1
Show InChI InChI=1S/C26H46O5/c1-6-7-8-9-10-11-24(28)30-19-26(18-27)15-14-23(25(29)31-26)13-12-22(16-20(2)3)17-21(4)5/h13,20-22,27H,6-12,14-19H2,1-5H3/b23-13+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
129n/an/an/an/an/an/an/an/a



Research Institute of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserine


J Med Chem 49: 2028-36 (2006)


Article DOI: 10.1021/jm0509391
BindingDB Entry DOI: 10.7270/Q27D2TQ1
More data for this
Ligand-Target Pair