BDBM50184503 CHEMBL207622::N-(2-((1-(4-(aminomethyl)phenyl)piperidin-4-yl)methylamino)ethyl)naphthalene-2-sulfonamide

SMILES: NCc1ccc(cc1)N1CCC(CNCCNS(=O)(=O)c2ccc3ccccc3c2)CC1

InChI Key: InChIKey=DSRLONQJJSLFPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase beta-1/beta-2 (Homo sapiens (Human))	BDBM50184503 (CHEMBL207622 | N-(2-((1-(4-(aminomethyl)phenyl)pip...) Show SMILES NCc1ccc(cc1)N1CCC(CNCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C25H32N4O2S/c26-18-20-5-8-24(9-6-20)29-15-11-21(12-16-29)19-27-13-14-28-32(30,31)25-10-7-22-3-1-2-4-23(22)17-25/h1-10,17,21,27-28H,11-16,18-19,26H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human beta tryptase				Bioorg Med Chem Lett 16: 2986-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.064 BindingDB Entry DOI: 10.7270/Q2QC0322
					More data for this Ligand-Target Pair