BDBM50184641 CHEMBL208575::[benzyloxycarbonylamino-(4-guanidino-phenyl)-methyl]-phosphonic acid bis-(4-ethyl-phenyl) ester trifluoro-acetic acid salt

SMILES: [#6]-[#6]-c1ccc(-[#8]P(=O)([#8]-c2ccc(-[#6]-[#6])cc2)[#6](-[#7]-[#6](=O)-[#8]-[#6]-c2ccccc2)-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])cc1

InChI Key: InChIKey=IFYMQFZWVLAXQB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50184641 (CHEMBL208575 | [benzyloxycarbonylamino-(4-guanidin...) Show SMILES [#6]-[#6]-c1ccc(-[#8]P(=O)([#8]-c2ccc(-[#6]-[#6])cc2)[#6](-[#7]-[#6](=O)-[#8]-[#6]-c2ccccc2)-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])cc1 Show InChI InChI=1S/C32H35N4O5P/c1-3-23-10-18-28(19-11-23)40-42(38,41-29-20-12-24(4-2)13-21-29)30(26-14-16-27(17-15-26)35-31(33)34)36-32(37)39-22-25-8-6-5-7-9-25/h5-21,30H,3-4,22H2,1-2H3,(H,36,37)(H4,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc£?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of human uPA by chromogenic assay using Cbz-Val-Gly-Arg-pNA as chromogenic substrate				Bioorg Med Chem Lett 16: 2886-90 (2006) Article DOI: 10.1016/j.bmcl.2006.03.002 BindingDB Entry DOI: 10.7270/Q22N51WR
					More data for this Ligand-Target Pair