BDBM50184645 CHEMBL209091::[benzyloxycarbonylamino-(4-guanidino-phenyl)-methyl]-phosphonic acid di-p-tolyl ester trifluoro-acetic acid salt

SMILES: [#6]-c1ccc(-[#8]P(=O)([#8]-c2ccc(-[#6])cc2)[#6](-[#7]-[#6](=O)-[#8]-[#6]-c2ccccc2)-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])cc1

InChI Key: InChIKey=AJFSGDNYRDNGAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50184645 (CHEMBL209091 | [benzyloxycarbonylamino-(4-guanidin...) Show SMILES [#6]-c1ccc(-[#8]P(=O)([#8]-c2ccc(-[#6])cc2)[#6](-[#7]-[#6](=O)-[#8]-[#6]-c2ccccc2)-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])cc1 Show InChI InChI=1S/C30H31N4O5P/c1-21-8-16-26(17-9-21)38-40(36,39-27-18-10-22(2)11-19-27)28(24-12-14-25(15-13-24)33-29(31)32)34-30(35)37-20-23-6-4-3-5-7-23/h3-19,28H,20H2,1-2H3,(H,34,35)(H4,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Wroc£?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of human uPA by chromogenic assay using Cbz-Val-Gly-Arg-pNA as chromogenic substrate				Bioorg Med Chem Lett 16: 2886-90 (2006) Article DOI: 10.1016/j.bmcl.2006.03.002 BindingDB Entry DOI: 10.7270/Q22N51WR
					More data for this Ligand-Target Pair