BindingDB logo
myBDB logout

null

SMILES: Cc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ncccc1C(F)(F)F

InChI Key: InChIKey=GHGDKTGPLQLVJX-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184732   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50184732
PNG
(4-methyl-N-(4-(3-(trifluoromethyl)pyridin-2-yl)phe...)
Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ncccc1C(F)(F)F
Show InChI InChI=1S/C20H15F3N2O/c1-13-4-6-15(7-5-13)19(26)25-16-10-8-14(9-11-16)18-17(20(21,22)23)3-2-12-24-18/h2-12H,1H3,(H,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Merck Sharp & Dohme

Curated by ChEMBL


Assay Description
Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assay

Bioorg Med Chem Lett 16: 2872-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.004
BindingDB Entry DOI: 10.7270/Q2959H50
More data for this
Ligand-Target Pair