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SMILES: Cc1ccc(cc1)-c1nc2cc(ccc2[nH]1)-c1ncccc1C(F)(F)F

InChI Key: InChIKey=GNJRIIPXLQFRMY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184735   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50184735
PNG
(2-p-tolyl-6-(3-(trifluoromethyl)pyridin-2-yl)-1H-b...)
Show SMILES Cc1ccc(cc1)-c1nc2cc(ccc2[nH]1)-c1ncccc1C(F)(F)F
Show InChI InChI=1S/C20H14F3N3/c1-12-4-6-13(7-5-12)19-25-16-9-8-14(11-17(16)26-19)18-15(20(21,22)23)3-2-10-24-18/h2-11H,1H3,(H,25,26)
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n/an/a 170n/an/an/an/an/an/a



Merck Sharp & Dohme

Curated by ChEMBL


Assay Description
Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assay

Bioorg Med Chem Lett 16: 2872-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.004
BindingDB Entry DOI: 10.7270/Q2959H50
More data for this
Ligand-Target Pair