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SMILES: FC(F)(F)c1cccnc1-c1ccc(NC(=O)c2ccccc2)cc1

InChI Key: InChIKey=ZVWJVFCCIBOKCF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184736   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50184736
PNG
(CHEMBL208870 | N-(4-(3-(trifluoromethyl)pyridin-2-...)
Show SMILES FC(F)(F)c1cccnc1-c1ccc(NC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C19H13F3N2O/c20-19(21,22)16-7-4-12-23-17(16)13-8-10-15(11-9-13)24-18(25)14-5-2-1-3-6-14/h1-12H,(H,24,25)
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Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Merck Sharp & Dohme

Curated by ChEMBL


Assay Description
Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assay

Bioorg Med Chem Lett 16: 2872-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.004
BindingDB Entry DOI: 10.7270/Q2959H50
More data for this
Ligand-Target Pair