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SMILES: Cc1cccnc1-c1ccc2c(c1)[nH]n(-c1ccc(cc1)C(F)(F)F)c2=O

InChI Key: InChIKey=NDCDEIBRKPCRDY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184740   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50184740
PNG
(6-(3-methylpyridin-2-yl)-2-(4-(trifluoromethyl)phe...)
Show SMILES Cc1cccnc1-c1ccc2c(c1)[nH]n(-c1ccc(cc1)C(F)(F)F)c2=O
Show InChI InChI=1S/C20H14F3N3O/c1-12-3-2-10-24-18(12)13-4-9-16-17(11-13)25-26(19(16)27)15-7-5-14(6-8-15)20(21,22)23/h2-11,25H,1H3
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n/an/a 180n/an/an/an/an/an/a



Merck Sharp & Dohme

Curated by ChEMBL


Assay Description
Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assay

Bioorg Med Chem Lett 16: 2872-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.004
BindingDB Entry DOI: 10.7270/Q2959H50
More data for this
Ligand-Target Pair