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SMILES: FC(F)(F)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccccn1

InChI Key: InChIKey=KQIDEDJHNOBDNP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184744   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50184744
PNG
(CHEMBL209112 | N-(4-(pyridin-2-yl)phenyl)-4-(trifl...)
Show SMILES FC(F)(F)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccccn1
Show InChI InChI=1S/C19H13F3N2O/c20-19(21,22)15-8-4-14(5-9-15)18(25)24-16-10-6-13(7-11-16)17-3-1-2-12-23-17/h1-12H,(H,24,25)
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Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Merck Sharp & Dohme

Curated by ChEMBL


Assay Description
Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assay

Bioorg Med Chem Lett 16: 2872-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.004
BindingDB Entry DOI: 10.7270/Q2959H50
More data for this
Ligand-Target Pair