BDBM50184912 CHEMBL206498::N-[3-[trans-4-[[[(3-chloro-4-fluorophenyl)amino]carbonyl][3-(4-methyl-1-piperazinyl)propyl]amino]bicyclo[3.1.0]hex-1-yl]-phenyl]methanesulfonamide

SMILES: CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2cccc(NS(C)(=O)=O)c2)C(=O)Nc2ccc(F)c(Cl)c2)CC1

InChI Key: InChIKey=PJOFDORDRUWYLO-KODFZCBSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50184912 (CHEMBL206498 | N-[3-[trans-4-[[[(3-chloro-4-fluoro...) Show SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2cccc(NS(C)(=O)=O)c2)C(=O)Nc2ccc(F)c(Cl)c2)CC1 Show InChI InChI=1S/C28H37ClFN5O3S/c1-33-13-15-34(16-14-33)11-4-12-35(27(36)31-21-7-8-25(30)24(29)18-21)26-9-10-28(19-23(26)28)20-5-3-6-22(17-20)32-39(2,37)38/h3,5-8,17-18,23,26,32H,4,9-16,19H2,1-2H3,(H,31,36)/t23-,26-,28-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	394	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in CHO cell				J Med Chem 49: 2294-310 (2006) Article DOI: 10.1021/jm050886n BindingDB Entry DOI: 10.7270/Q2HQ3ZGH
					More data for this Ligand-Target Pair