BDBM50185041 CHEMBL380429::N-(4-phenoxyphenyl)-N'-[1-(2-azepan-1-yl-ethyl)-1H-indazol-5-yl]urea

SMILES: O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2n(CCN3CCCCCC3)ncc2c1

InChI Key: InChIKey=QHGDIVQNYIWTEJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50185041 (CHEMBL380429 | N-(4-phenoxyphenyl)-N'-[1-(2-azepan...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2n(CCN3CCCCCC3)ncc2c1 Show InChI InChI=1S/C28H31N5O2/c34-28(30-23-10-13-26(14-11-23)35-25-8-4-3-5-9-25)31-24-12-15-27-22(20-24)21-29-33(27)19-18-32-16-6-1-2-7-17-32/h3-5,8-15,20-21H,1-2,6-7,16-19H2,(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from MCHr1 expressed in IMR32 (I3.4.2) cells				J Med Chem 49: 2339-52 (2006) Article DOI: 10.1021/jm0512286 BindingDB Entry DOI: 10.7270/Q24F1Q9F
					More data for this Ligand-Target Pair