BDBM50185077 2-(3,4-dimethoxybenzamido)-4,5-dimethylthiophene-3-carboxamide::CHEMBL210860

SMILES: COc1ccc(cc1OC)C(=O)Nc1sc(C)c(C)c1C(N)=O

InChI Key: InChIKey=LIHHSRQLJBNWMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50185077 (2-(3,4-dimethoxybenzamido)-4,5-dimethylthiophene-3...) Show SMILES COc1ccc(cc1OC)C(=O)Nc1sc(C)c(C)c1C(N)=O Show InChI InChI=1S/C16H18N2O4S/c1-8-9(2)23-16(13(8)14(17)19)18-15(20)10-5-6-11(21-3)12(7-10)22-4/h5-7H,1-4H3,(H2,17,19)(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem Lett 16: 3282-6 (2006) Article DOI: 10.1016/j.bmcl.2006.03.032 BindingDB Entry DOI: 10.7270/Q2R49QCV
					More data for this Ligand-Target Pair