BDBM50185088 2-(3,4-dimethoxybenzamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide::CHEMBL209016

SMILES: COc1ccc(cc1OC)C(=O)Nc1sc2CCCCCc2c1C(N)=O

InChI Key: InChIKey=OBTRHSACGAHRDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50185088 (2-(3,4-dimethoxybenzamido)-5,6,7,8-tetrahydro-4H-c...) Show SMILES COc1ccc(cc1OC)C(=O)Nc1sc2CCCCCc2c1C(N)=O Show InChI InChI=1S/C19H22N2O4S/c1-24-13-9-8-11(10-14(13)25-2)18(23)21-19-16(17(20)22)12-6-4-3-5-7-15(12)26-19/h8-10H,3-7H2,1-2H3,(H2,20,22)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem Lett 16: 3282-6 (2006) Article DOI: 10.1016/j.bmcl.2006.03.032 BindingDB Entry DOI: 10.7270/Q2R49QCV
					More data for this Ligand-Target Pair