BDBM50185223 (S)-3-(1H-benzo[d]imidazol-2-yl)-5,6-dichloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one::CHEMBL209256

SMILES: Clc1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)c(N[C@@H]3CN4CCC3CC4)c2c1Cl

InChI Key: InChIKey=HGIMWJDEACPWKP-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50185223 ((S)-3-(1H-benzo[d]imidazol-2-yl)-5,6-dichloro-4-(q...) Show SMILES Clc1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)c(N[C@@H]3CN4CCC3CC4)c2c1Cl |wU:20.21,TLB:19:20:24.23:26.27,(3.37,-44,;4.71,-44.76,;4.71,-46.31,;6.04,-47.08,;7.37,-46.31,;8.71,-47.08,;10.06,-46.3,;11.39,-47.07,;10.05,-44.75,;11.38,-43.97,;12.78,-44.6,;13.81,-43.46,;15.35,-43.46,;16.12,-42.12,;15.34,-40.78,;13.8,-40.79,;13.04,-42.12,;11.53,-42.45,;8.7,-43.97,;8.69,-42.43,;7.74,-41.22,;7.47,-39.83,;6.12,-39.23,;4.65,-39.87,;4.85,-41.25,;6.38,-40.59,;6.63,-38.7,;6.19,-37.59,;7.37,-44.76,;6.03,-43.99,;6.03,-42.46,)| Show InChI InChI=1S/C23H21Cl2N5O/c24-13-5-6-16-18(20(13)25)21(26-17-11-30-9-7-12(17)8-10-30)19(23(31)29-16)22-27-14-3-1-2-4-15(14)28-22/h1-6,12,17H,7-11H2,(H,27,28)(H2,26,29,31)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of CHK1				Bioorg Med Chem Lett 16: 3121-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.059 BindingDB Entry DOI: 10.7270/Q2765DXT
					More data for this Ligand-Target Pair