BDBM50185501 7-(2,4-difluorophenyl)-3-(2-fluorophenyl)-2-((2-methyl-2H-1,2,4-triazol-3-yl)methoxy)pyrazolo[1,5-d][1,2,4]triazine::CHEMBL376975

SMILES: Cn1ncnc1COc1nn2c(nncc2c1-c1ccccc1F)-c1ccc(F)cc1F

InChI Key: InChIKey=RFOXASLOAHSVQO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185501   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50185501 (7-(2,4-difluorophenyl)-3-(2-fluorophenyl)-2-((2-me...) Show SMILES Cn1ncnc1COc1nn2c(nncc2c1-c1ccccc1F)-c1ccc(F)cc1F |(24.1,-46.81,;22.58,-46.59,;21.5,-47.7,;20.12,-47.02,;20.34,-45.49,;21.87,-45.22,;22.64,-43.89,;21.88,-42.56,;22.65,-41.22,;24.19,-41.07,;24.51,-39.56,;25.86,-38.79,;25.85,-37.24,;24.51,-36.47,;23.18,-37.25,;23.18,-38.78,;22.03,-39.81,;20.69,-39.05,;20.7,-37.51,;19.36,-36.75,;18.03,-37.52,;18.04,-39.07,;19.37,-39.83,;19.39,-41.37,;27.19,-39.56,;27.19,-41.1,;28.52,-41.87,;29.86,-41.1,;31.19,-41.86,;29.85,-39.55,;28.52,-38.79,;28.51,-37.25,)| Show InChI InChI=1S/C21H14F3N7O/c1-30-18(25-11-27-30)10-32-21-19(13-4-2-3-5-15(13)23)17-9-26-28-20(31(17)29-21)14-7-6-12(22)8-16(14)24/h2-9,11H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]Ro15-1788 binding to human recombinant GABA-Aalpha3 plus beta3gamma2 receptor expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 3550-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.081 BindingDB Entry DOI: 10.7270/Q21J99CH
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