BDBM50185520 3-(2,3-difluorophenyl)-7-(2-fluorophenyl)-2-((2-methyl-2H-1,2,4-triazol-3-yl)methoxy)pyrazolo[1,5-d][1,2,4]triazine::CHEMBL211286

SMILES: Cn1ncnc1COc1nn2c(nncc2c1-c1cccc(F)c1F)-c1ccccc1F

InChI Key: InChIKey=WQCOYHWSQLUYIH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50185520 (3-(2,3-difluorophenyl)-7-(2-fluorophenyl)-2-((2-me...) Show SMILES Cn1ncnc1COc1nn2c(nncc2c1-c1cccc(F)c1F)-c1ccccc1F |(-3.94,-4.45,;-5.46,-4.23,;-6.53,-5.33,;-7.92,-4.65,;-7.7,-3.13,;-6.17,-2.86,;-5.4,-1.53,;-6.16,-.19,;-5.39,1.14,;-3.85,1.29,;-3.53,2.8,;-2.18,3.57,;-2.19,5.12,;-3.53,5.89,;-4.85,5.12,;-4.86,3.58,;-6.01,2.55,;-7.35,3.31,;-7.34,4.85,;-8.68,5.61,;-10.01,4.84,;-10,3.29,;-11.33,2.51,;-8.66,2.53,;-8.65,.99,;-.85,2.8,;-.85,1.26,;.48,.5,;1.82,1.27,;1.81,2.81,;.48,3.58,;.47,5.12,)| Show InChI InChI=1S/C21H14F3N7O/c1-30-17(25-11-27-30)10-32-21-18(13-6-4-8-15(23)19(13)24)16-9-26-28-20(31(16)29-21)12-5-2-3-7-14(12)22/h2-9,11H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]Ro15-1788 binding to human recombinant GABA-Aalpha3 plus beta3gamma2 receptor expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 3550-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.081 BindingDB Entry DOI: 10.7270/Q21J99CH
					More data for this Ligand-Target Pair