null

SMILES: CN1CCN(CC1)c1nccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1

InChI Key: InChIKey=JLFKBORRFRIWDY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50185537 (2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-4-(...) Show SMILES CN1CCN(CC1)c1nccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1 Show InChI InChI=1S/C22H23ClN6O/c1-28-10-12-29(13-11-28)21-17-14-19(25-18(17)8-9-24-21)22-26-20(27-30-22)7-4-15-2-5-16(23)6-3-15/h2-3,5-6,8-9,14,25H,4,7,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]N/OFQ from ORL1 receptor transfected in CHO cells				Bioorg Med Chem Lett 16: 3569-73 (2006) Article DOI: 10.1016/j.bmcl.2006.03.086 BindingDB Entry DOI: 10.7270/Q2N879D1
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185537 (2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-4-(...) Show SMILES CN1CCN(CC1)c1nccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1 Show InChI InChI=1S/C22H23ClN6O/c1-28-10-12-29(13-11-28)21-17-14-19(25-18(17)8-9-24-21)22-26-20(27-30-22)7-4-15-2-5-16(23)6-3-15/h2-3,5-6,8-9,14,25H,4,7,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity against ORL1 receptor by GTPgammaS assay				Bioorg Med Chem Lett 16: 3569-73 (2006) Article DOI: 10.1016/j.bmcl.2006.03.086 BindingDB Entry DOI: 10.7270/Q2N879D1
					More data for this Ligand-Target Pair