null
SMILES: COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1nc(co1)C(=O)OC
InChI Key: InChIKey=FZESJEAHFRNXME-PJDXPPHMSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50185614 (CHEMBL377182 | methyl 2-((2S,4aR,6aR,7R,9S,10aS,10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Iowa Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor | Bioorg Med Chem Lett 16: 3170-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.062 BindingDB Entry DOI: 10.7270/Q2CR5SZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50185614 (CHEMBL377182 | methyl 2-((2S,4aR,6aR,7R,9S,10aS,10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Iowa Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor | Bioorg Med Chem Lett 16: 3170-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.062 BindingDB Entry DOI: 10.7270/Q2CR5SZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50185614 (CHEMBL377182 | methyl 2-((2S,4aR,6aR,7R,9S,10aS,10...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Iowa Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor | Bioorg Med Chem Lett 16: 3170-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.062 BindingDB Entry DOI: 10.7270/Q2CR5SZK | |||||||||||
More data for this Ligand-Target Pair |