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SMILES: Cc1ccc(cc1)-c1ccc(o1)C(=O)n1cncn1

InChI Key: InChIKey=GQGOFMQNEKOZBA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185727   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50185727
PNG
(CHEMBL3823288)
Show SMILES Cc1ccc(cc1)-c1ccc(o1)C(=O)n1cncn1
Show InChI InChI=1S/C14H11N3O2/c1-10-2-4-11(5-3-10)12-6-7-13(19-12)14(18)17-9-15-8-16-17/h2-9H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 5.60E+3n/an/an/an/an/an/a



South China Agricultural University

Curated by ChEMBL


Assay Description
Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins

Bioorg Med Chem Lett 26: 3632-5 (2016)


BindingDB Entry DOI: 10.7270/Q27946MZ
More data for this
Ligand-Target Pair