BDBM50185730 CHEMBL3823761

SMILES: Fc1ccc(-c2ccc(o2)C(=O)n2cncn2)c(F)c1

InChI Key: InChIKey=WVXDFOMEBDMOSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50185730 (CHEMBL3823761) Show SMILES Fc1ccc(-c2ccc(o2)C(=O)n2cncn2)c(F)c1 Show InChI InChI=1S/C13H7F2N3O2/c14-8-1-2-9(10(15)5-8)11-3-4-12(20-11)13(19)18-7-16-6-17-18/h1-7H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 26: 3632-5 (2016) BindingDB Entry DOI: 10.7270/Q27946MZ
					More data for this Ligand-Target Pair