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SMILES: Clc1ccc(cc1)-c1ccc(o1)C(=O)n1cncn1

InChI Key: InChIKey=FOEODFZFFKMYDG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185736   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50185736
PNG
(CHEMBL3823501)
Show SMILES Clc1ccc(cc1)-c1ccc(o1)C(=O)n1cncn1
Show InChI InChI=1S/C13H8ClN3O2/c14-10-3-1-9(2-4-10)11-5-6-12(19-11)13(18)17-8-15-7-16-17/h1-8H
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



South China Agricultural University

Curated by ChEMBL


Assay Description
Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins

Bioorg Med Chem Lett 26: 3632-5 (2016)


BindingDB Entry DOI: 10.7270/Q27946MZ
More data for this
Ligand-Target Pair