BDBM50185743 CHEMBL3823585
SMILES: Fc1ccc(-c2ccc(o2)C(=O)n2cccn2)c(F)c1
InChI Key: InChIKey=QIQAVNWXJDJYRX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50185743 (CHEMBL3823585) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University Curated by ChEMBL | Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins | Bioorg Med Chem Lett 26: 3632-5 (2016) BindingDB Entry DOI: 10.7270/Q27946MZ | |||||||||||
More data for this Ligand-Target Pair |