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BDBM50185749 CHEMBL3823140

SMILES: Clc1ccc(cc1)-c1ccc(o1)C(=O)n1cccn1

InChI Key: InChIKey=CLDQEQWTPFQNRO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185749   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50185749
PNG
(CHEMBL3823140)
Show SMILES Clc1ccc(cc1)-c1ccc(o1)C(=O)n1cccn1
Show InChI InChI=1S/C14H9ClN2O2/c15-11-4-2-10(3-5-11)12-6-7-13(19-12)14(18)17-9-1-8-16-17/h1-9H
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 5.60E+3n/an/an/an/an/an/a



South China Agricultural University

Curated by ChEMBL


Assay Description
Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins

Bioorg Med Chem Lett 26: 3632-5 (2016)


BindingDB Entry DOI: 10.7270/Q27946MZ
More data for this
Ligand-Target Pair