BDBM50185806 3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL378633

SMILES: C(C1CCCCCCC1)N1CCC(CC1)c1c[nH]c2ncccc12

InChI Key: InChIKey=PMTRYEMIYDPQRC-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185806   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50185806 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-pyrrolo[...) Show SMILES C(C1CCCCCCC1)N1CCC(CC1)c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H31N3/c1-2-4-7-17(8-5-3-1)16-24-13-10-18(11-14-24)20-15-23-21-19(20)9-6-12-22-21/h6,9,12,15,17-18H,1-5,7-8,10-11,13-14,16H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185806 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-pyrrolo[...) Show SMILES C(C1CCCCCCC1)N1CCC(CC1)c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H31N3/c1-2-4-7-17(8-5-3-1)16-24-13-10-18(11-14-24)20-15-23-21-19(20)9-6-12-22-21/h6,9,12,15,17-18H,1-5,7-8,10-11,13-14,16H2,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185806 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-pyrrolo[...) Show SMILES C(C1CCCCCCC1)N1CCC(CC1)c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H31N3/c1-2-4-7-17(8-5-3-1)16-24-13-10-18(11-14-24)20-15-23-21-19(20)9-6-12-22-21/h6,9,12,15,17-18H,1-5,7-8,10-11,13-14,16H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50185806 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-pyrrolo[...) Show SMILES C(C1CCCCCCC1)N1CCC(CC1)c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H31N3/c1-2-4-7-17(8-5-3-1)16-24-13-10-18(11-14-24)20-15-23-21-19(20)9-6-12-22-21/h6,9,12,15,17-18H,1-5,7-8,10-11,13-14,16H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair