BindingDB PrimarySearch

BDBM50185931 8-Octyl-benzolactam-V9::CHEMBL206866

SMILES: CCCCCCCCc1cccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CCc12

InChI Key: InChIKey=IDVIOLNZWSXZGL-REWPJTCUSA-N

Data: 23 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50185931
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C, eta (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCeta C1B domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	144	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC eta-C1B				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC delta-C1B				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCdelta C1B domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC theta-C1B				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCtheta C1B domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCepsilon C1B domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC epsilon-C1B				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC gamma-C1B				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCalpha C1B domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCbeta C1A domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC beta-C1A				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCbeta C1B domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCgamma C1A domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCalpha C1A domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC beta-C1B				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC eta-C1A				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC alpha-C1A				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC delta-C1A				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC gamma-C1A				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCgamma C1A domain				J Med Chem 51: 46-56 (2008) Article DOI: 10.1021/jm0706719 BindingDB Entry DOI: 10.7270/Q2445M7Q
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC epsilon-C1A				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50185931 (8-Octyl-benzolactam-V9 \| CHEMBL206866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]phorbol 12,13-dibutyrate from PKC alpha-C1B				J Med Chem 49: 2681-8 (2006) Article DOI: 10.1021/jm050857c BindingDB Entry DOI: 10.7270/Q2BR8RSR
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair